Differential elimination of rDNA genes in bobbed mutants of Drosophila melanogaster.
نویسندگان
چکیده
منابع مشابه
Influence of the RNA content on oogenesis in the bobbed mutants of Drosophila melanogaster.
Developing egg chambers of Drosophila melanogaster (wild-type and bobbed mutants) have been examined for their nucleic acid content by cytophotometric methods. No differences were observed in the total DNA and RNA content of the egg chambers at all stages between the bobbed mutants and the wild type. It is shown that the process of oogenesis in bobbed females is prolonged, and that this prolong...
متن کاملRegulation of ribosomal RNA and 5s RNA synthesis in Drosophila melanogaster. I. Bobbed mutants.
Analysis of the rates and amounts of rRNA and 5s RNA synthesized in Drosophila melanogaster bobbed mutants was done by using acrylamide-gel electrophoresis. The results show that the amounts of rRNA synthesized are constant, although the rates of rRNA synthesis in bb's are reduced to 30% of the wild-type level. The rates of synthesis of 5s RNA were constant. The rate of synthesis of the two kin...
متن کاملExchanges at the bobbed locus of Drosophila melanogaster.
I N this paper evidence will be presented that crossing over at the bobbed (bb) locus of Drosophih melanogaster generates a variety of mutant alleles. Some of these alleles are distinguishable from one another and their parental alleles in the degree of their effect as judged by bristle size, abdominal etching and viability. These observations are in harmony with the genetic organization of the...
متن کاملAutosomal modifiers of the bobbed phenotype are a major component of the rDNA magnification paradox in Drosophila melanogaster.
rDNA magnification in Drosophila melanogaster is defined experimentally as the ability of bb/Ybb- males to produce exceptional progeny that are wild type with respect to rDNA associated phenotypes. Here, we show that some of these bobbed-plus progeny result not from genetic reversion at the bb locus but rather from variants at two or more autosomal loci that ameliorate the bobbed phenotype of r...
متن کاملOne-step and stepwise magnification of a bobbed lethal chromosome in Drosophila melanogaster.
Bobbed lethal (bbl) chromosomes carry too few ribosomal genes for homozygous flies to be viable. Reversion of bbl chromosomes to bb or nearly bb+ occurs under magnifying conditions at a low frequency in a single generation. These reversions occur too rapidly to be accounted for by single unequal sister chromatid exchanges and seem unlikely to be due to multiple sister strand exchanges within a ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1986
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.6.4.1023